From 1919 to 1924, the academic painter Omer Mujadžić studied at the Higher Art School (later the Academy of Fine Arts in Zagreb) in the class of Ferdo Kovačević and Ljubo Babić. He graduated in 1924 in Ljuba Babić's class. From 1925 to 1926, he stayed in Paris and continued his studies at the Ecole des Beaux-Arts. From 1931 to 1973, he was a professor at the Academy of Fine Arts in Zagreb. He is a member of the group "Zemlja" (1929). He has been a corresponding member of JAZU since 1977.

At the end of the 1920s, he made a special neoclassical contribution to the third period of the Spring Salon, but soon, as one of the founders and briefly a member of the Association of Artists "Zemlja" (exhibited at the first exhibition in 1929), he turned to engaged art. His interest focuses on the depiction of children's work or scenes of peasants and workers, which he elevates to symbols, and in scenes of urban everyday life, nightlife from the periphery, as well as industrial plants, he is more preoccupied with form problems and realistic depiction. Since the 1930s, he has completely moved away from engaged art. In the 1930s, he approached colorism by gradually softening the forms, freeing the strokes, more accentuated light and more intense colors. In addition to idealized scenes from the countryside and female characters in everyday surroundings, nostalgic interiors related to childhood, there is a special series of large female nudes with pronounced plasticity and chromatically rich portraits. Having created the original synthesis of modern painting, he was an important protagonist of the Croatian art scene.